The program takes place in the fictional capital city of Moralton, in the fictional Bible Belt state "Statesota." According to the globe shown in the opening credits, Moralton is in the exact center of the United States, with the town's church at the exact center of the town.
The main character is Orel Puppington, a student at Alfred G. Diorama Elementary School, who tries to live by the Protestant Christian moral code as articulated in church or by his father, Clay. Orel naïvely follows this code to illogical extremes, with disastrous results. The series is a parody of the archetypes of 1950s American suburban life, modern-day WASP culture and Christianity.