Lil' Bush takes place in an alternate reality version of modern times, where George H.W. Bush is president and George W. Bush ("Lil' Bush" on the show) as well as other major modern politicians (many of them members of real-life George W. Bush's staff) are all children attending Beltway Elementary School. Issues the current Bush Administration is involved in---for example, the Iraq War---are transferred to the elder Bush, but feature the younger Bush interacting with them in various ways.