The series chronicles a six-year-old girl named Doc McStuffins who, one day, wants to become a doctor like her mother. As a kid, she "pretends" to be a doctor by fixing up toys and dolls. When she puts on her stethoscope, something magical happens: toys, dolls and stuffed animals come to life and she can communicate with them. With a little help from her stuffed animal friends, Stuffy, Hallie, Lambie and Chilly, Doc helps toys "feel better" by giving them check-ups. Each 11-minute episode includes original songs and the "Time for your Check-up" song. During ending credits, Doc gives advice to viewers about staying healthy.