Crusade is a spin-off TV show from J. Michael Straczynski's Babylon 5. Its plot is set five years after the events of Babylon 5, and just after the movie A Call to Arms. A race called the Drakh have released a nanovirus plague on Earth, which will destroy all life on Earth within five years if it is not stopped. To that end, the destroyer Excalibur has been sent out to look for anything that could help the search for a cure.